Sulfamethazine
Macluumaadka aasaasiga ah:
Magaca Alaabta: Sulfamethazine
Magaca: sulfadimethylpyrimidine
Qaabka kiimikada: C12H14N4O2S
Qaab-dhismeedka:
Miisaanka molecular: 278.33
CAS lambarka gelitaanka: 57-68-1
EINECS lambarka gelitaanka: 200-346-4
sifooyinka jirka iyo kiimikaad
Cufnaanta: 1.392g/cm3
Barta dhalaalka: 197°C
Barta karkarinta: 526.2ºC
Barta toosh: 272.1ºC
Muuqaalka: budada crystalline cad
Solubility: ku dhawaad aan lagu milmi karin biyaha, aan lagu milmi karin ether, si fudud ugu milmi aashitada ama milanka alkali
Sulfadiazine waa antibiyootig sulfanilamide oo leh spectrum bakteeriyada la mid ah sulfadiazine. Waxay leedahay saameyn liddi ku ah bakteeriyada enterobacteriaceae sida Staphylococcus aureus non-zymogenic, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, iwm. Neisseria gonorrhoea, Neisseria meningitidis. Si kastaba ha ahaatee, caabbinta bakteeriyada ee alaabta ayaa kordhay, gaar ahaan streptococcus, Neisseria iyo bakteeriyada Enterobacteriaceae. Sulfonamides waa wakiilada bacteriostatic ballaaran, oo la mid ah qaab dhismeedka p-aminobenzoic acid (PABA), kaas oo si tartan ah ugu dhaqmi kara dihydrofolate synthetase ee bakteeriyada, taas oo ka hortagaysa PABA in loo isticmaalo sida alaabta ceeriin si loo soo saaro folate ay u baahan tahay bakteeriyada iyo yaraynta qadarka dheef-shiid kiimikaad firfircoon tetrahydrofolate. Tan dambe waa walax lagama maarmaan u ah isku-dhafka purines, thymidine nucleosides iyo deoxyribonucleic acid (DNA), sidaas darteed waxay joojisaa koritaanka iyo taranka bakteeriyada.
Waxaa inta badan loo isticmaalaa infekshannada fudud ee ay keento bakteeriyada xasaasiga ah, sida caabuqa fudud ee kaadi mareenka hoose ee degdega ah, otitis media ba'an iyo caabuq unug jilicsan oo maqaarka ah.
