7-Amino-3-cephem-4-carboxylic acid
Macluumaadka aasaasiga ah:
Ingiriis oo loo yaqaan:
7-ANCA;7-AMOCA;(6R,7R)-7-AMIno-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylicAcid;7-NACA;7-NACA,7-ANCA;7-ANCAChemicalbookimpurity;CeftizoximeImpurity9;CeftizoximeImpurity16;Ceftizoximeintermediate(7-anca);7-amino-3-cephem-4-carboxylicacid
Lambarka CAS: 36923-17-8
Qaaciddada molecular: C7H8N2O3S
Miisaanka molecular: 200.21
EINECS nambarka: 609-312-7
Qaab-dhismeedka:
Qaybaha la xidhiidha: Dhexdhexaadiyeyaasha dabiiciga ah; Dhexdhexaadiyeyaasha daawada; Qalabka ceeriin ee dawooyinka.
Meesha dhalaalka: 215-218°C
Barta karkarinta: 536.9± 50.0 °C (La saadaaliyay)
Cufnaanta: 1.69± 0.1g /cm3(La saadaaliyay)
Tusmada dib-u-celinta: 1.735 (qiyaas)
Barta iftiimaya: 278.508°C
Solubility: Ku milma dareeraha aashitada ah (wax yar, kuleyl), DMSO (wax yar). Guryaha: Budada crystalline cad ama cad.
Cadaadiska uumiga: 0mmHg at 25°C
| qeexid | unug | heerka |
| Muuqashada | Budada crystalline cad ama cad | |
| Nuxurka ugu muhiimsan | % | ≥98.5% |
| Qoyaanka | % | ≤1 |
| Mono hybrid | % | ≤0.5 |
| Isku darka guud | % | ≤1 |
Cephalosporin, oo loo isticmaalo dhexdhexaadinta cefbutan iyo cefazoxime.
Sulfuric acid xoog leh (104.3mL, 1.92mol) ayaa lagu daray saddex dhalo, ka dibna isophthalic acid (40g, 0.24mol) ayaa lagu daray, walaaqay oo kululeeyay ilaa 60 ℃, oo lagu hayo 0.5h, iyo 60% nitric acid (37.8g, 0.36mol) hoos u dhac ah ayaa lagu daray. Ku dar 2 saacadood gudahood. Intaa ka dib, falcelinta ilaalinta kulaylka 60 ℃ 2 saacadood. Ku qabooji heer ka hooseeya 50 ° C, ka dibna ku dar 100 ml oo biyo ah. Maaddada ayaa la qaboojiyey heerkulka qolka, lagu shubay shaandhada, bamgareynta si loo soo saaro aashitada qashinka, keega filtarka ayaa lagu dhaqay biyo, oo la miiray si dib loogu celiyo, iyo badeecada cad waxay ahayd 34.6 garaam, wax-soo-saarku wuxuu ahaa 68.4%.
20Kg ama 25Kg/ baaldi, baaldi kartoon ah, oo lagu dahaadhay lakab cad iyo bac madow oo polyetylen ah. 2℃-8℃ qalalan, meel qabow, ka fog kaydinta iftiinka, shaqaynaysa 2 sano.
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