7-Amino-3-cephem-4-carboxylic acid
Macluumaadka aasaasiga ah:
Ingiriis oo loo yaqaan:
7-ANCA;7-AMOCA;(6R,7R)-7-AMIno-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylicAcid;7-NACA;7- NACA,7-ANCA;7-ANCAChemicalbookimpurity;CeftizoximeImpurity9;CeftizoximeImpurity16;Ceftizoximeintermediate(7-anca);7-amino-3-cephem-4-carboxylicacid
Lambarka CAS: 36923-17-8
Qaaciddada molecular: C7H8N2O3S
Miisaanka molecular: 200.21
EINECS nambarka: 609-312-7
Qaab-dhismeedka:
Qaybaha la xidhiidha: Dhexdhexaadiyeyaasha dabiiciga ah; Dhexdhexaadiyeyaasha daawada; Qalabka ceeriin ee dawooyinka.
Meesha dhalaalka: 215-218°C
Barta karkarinta: 536.9 ± 50.0 °C (La saadaaliyay)
Cufnaanta: 1.69± 0.1g /cm3(La saadaaliyay)
Tusmada dib-u-celinta: 1.735 (qiyaas)
Barta iftiimaya: 278.508°C
Solubility: Ku milmay xal aashito ah (wax yar, kuleyl), DMSO (wax yar). Guryaha: Budada crystalline cad ama cad.
Cadaadiska uumiga: 0mmHg at 25°C
| qeexid | unug | heerka |
| Muuqashada | Budada crystalline cad ama cad | |
| Nuxurka ugu muhiimsan | % | ≥98.5% |
| Qoyaanka | % | ≤1 |
| Mono hybrid | % | ≤0.5 |
| Isku darka guud | % | ≤1 |
Cephalosporin, oo loo isticmaalo dhexdhexaadinta cefbutan iyo cefazoxime.
Sulfuric acid (104.3mL, 1.92mol) ayaa lagu daray saddex dhalo, ka dibna isophthalic acid (40g, 0.24mol) ayaa lagu daray, walaaqay oo la kuley 60 ℃, oo lagu hayo 0.5h, iyo 60% nitric acid (37.8g, 0.36) mol) ayaa lagu daray si loo xakameeyo heerka dardargelinta dhibicda. Ku dar 2 saacadood gudahood. Intaa ka dib, falcelinta ilaalinta kulaylka 60 ℃ 2 saacadood. Ku qabooji heer ka hooseeya 50 ° C, ka dibna ku dar 100 ml oo biyo ah. Maaddada ayaa la qaboojiyey heerkulka qolka, lagu shubay shaandhada, bamgareynta si loo soo saaro aashitada qashinka, keega shaandhada ayaa lagu dhaqay biyo, daadi si dib loogu celiyo, iyo badeecada cad waxay ahayd 34.6 garaam, wax-soo-saarku wuxuu ahaa 68.4%.
20Kg ama 25Kg/ baaldi, baaldi kartoon ah, oo lagu dahaadhay lakab cad iyo bac madow oo polyetylen ah. 2℃-8℃ qalalan, meel qabow, ka fog kaydinta iftiinka, shaqaynaysa 2 sano.
