2-methyl-5-nitroimidazole
Macluumaadka aasaasiga ah:
Magaca kiimikada: 2-methyl-5-nitroimidazole;
Magaca Ingiriisiga: 2-Methyl-5-nitroimidazole;
Lambarka CAS: 88054-22-2
Qaaciddada molecular: C4H5N3O2
Miisaanka molecular: 127.1
EINECS nambarka: 618-108-7
Qaab-dhismeedka:
Qaybaha la xidhiidha: alaabta ceeriin; Dhexdhexaadiyeyaasha daawada; Qalabka ceeriin ee dawooyinka.
Cufnaanta:1.4± 0.1g/cm3
Barta karkarinta:399.5±15.0 °C at 760mmHg
Barta dhalaalka: 252-254ºC
Dhibicda Flash: 195.4±20.4 °C
Tirada saxda ah: 127.038177
PSA:74.50000 LogP:-0.10
Muuqashada: crystal cad
Cadaadiska uumiga:0.0±0.9mmHg at 25°C
Tusmada dib-u-celinta: 1.592
Xaaladaha kaydinta: lagu xidhay meel qabow oo qalalan oo ah 0-6 ºC
Xasilooni: ma qudhmi doonto marka la isticmaalo oo lagu kaydiyo si waafaqsan xeerarka.
| qeexid | unug | heerka |
| Muuqashada | Sida budo cad ama huruud ah | |
| Nuxurka | % | ≥99% |
| Qoyaanka | % | ≤0.3 |
| Sulfate | % | ≤0.3 |
Inta badan loo isticmaalo in synthesize metronidazole, dimetazole iyo daawooyinka kale ee dhexdhexaadka ah.
Waxaa lagu helaa nitration of 2-methylimidazole. Ku rid sulfuric acid, 2-methylimidazole iyo sodium sulfate dheriga falcelinta, walaaq oo kulayl, ku dar nitric acid 150-160 ℃, isku dar, raac falcelinta sanduuqa 1 saac. Ka saar heerkulka ilaa 140 ℃ hoos, ka dib markaad ku darto biyo leh biyaha ammonia si aad u hagaajisid pH ilaa 3.5-4, crystallization. Cadaadis, ku dhaq si dhexdhexaad ah, engegan, 2-methyl-5-nitroimidazole.
25k boorso warqad kraft ama bac tolan (58 × 110) lagu dahaadhay bac balaastik ah, 250kg bac dhoofinta (100 × 80); Sida waafaqsan shuruudaha macaamiisha;
Kaydinta la xidhay, lagu kaydiyay bakhaar qabow, mugdi ah, qalalan, kaydinta iyo gaadiidka waa inay noqdaan iftiin, si looga hortago burburka iyo qoyaanka, si adag ayaa loo mamnuucay daawooyinka isku dhafan.
Habka wax soo saarka: Waxaa lagu helaa nitration of 2-methylimidazole. Ku rid sulfuric acid, 2-methylimidazole iyo sodium sulfate dheriga falcelinta, walaaq oo kulayl, ku dar nitric acid 150-160 ℃, isku dar, raac falcelinta sanduuqa 1 saac. Ka saar heerkulka ilaa 140 ℃ hoos, ka dib markaad ku darto biyo leh biyaha ammonia si aad u hagaajisid pH ilaa 3.5-4, crystallization. Cadaadis, ku dhaq si dhexdhexaad ah, engegan, 2-methyl-5-nitroimidazole.
